Anti-inflammatory Properties of Mitragyna Speciosa Extract

Authors

  • Raja Aziddin R.E
  • Mustafa M.R
  • Mohamed Z
  • Mohd. M.A

Abstract

The anti-inflammatory property of the alkaloid extract from the leaves of Mitragyna speciosa was evaluated on the basis of the inhibitory effect of the extract on carrageenan-induced hind paw edema in rat. This extract when administered by intra peritoneal injection at a concentration of 50 mg/kg produced almost 100% inhibition of the carrageenan-induced paw edema 1 hour after administration. The inhibition was maintained at about 60%, 7 hours after administration. These findings suggest that the alkaloid extracts of the leaves of Mitragyna speciosa possess potent anti-inflammatory properties.

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Published

31-01-2005

Issue

Vol. 24 No. 1 (2005)

Section

Original Articles

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